Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp122 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2013

Effects of long-term oral administration with methimazole on femur properties in male Wistar rats

Tatara Marcin , Golynski Marcin , Radzki Radoslaw , Bienko Marek , Krupski Witold

Methimazol is an antithyroid drug for treatment of hyperthyroidism. Methimazol inhibits the enzyme thyroperoxidase participating in thyroid hormone synthesis and reduces triiodothyronine (T3) and thyroxine (T4) blood concentrations. The study was performed to determine effects of 90-day long oral administration with methimazol on femur properties isolated from male Wistar rats. The first group (n=6) consisted of control rats. The experimental rat...